CellChorus provides the TIMING™ platform, a high‑throughput nanowell imaging system that uses visual AI to track and quantify migration, activation, cell‑cell interactions, cytotoxicity, and survival of thousands of individual immune cells in real time. The workflow generates single‑cell functional datasets that can be linked to multi‑omic profiling such as single‑cell RNA‑seq or flow cytometry, enabling researchers to identify and select the most effective cell candidates for immunotherapy development.
Funding
$4.9M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
AVBIN+1Founders
Product
Problem
Researchers lack tools to simultaneously monitor the movement, activation, interactions, cytotoxicity, and survival of thousands of individual immune cells over time, making it difficult to identify the most effective cell candidates for therapy development and to link functional behavior with molecular phenotypes.
Solution
CellChorus offers the TIMING™ (Time‑lapse Imaging Microscopy in Nanowell Grids) platform, which combines high‑throughput nanowell imaging with visual AI to track and quantify dynamic cellular behaviors at single‑cell resolution. The workflow loads cryopreserved effector and target cells into nanowell arrays, captures fluorescent time‑lapse images, and uses AI‑driven segmentation and tracking to measure migration, cell‑cell contacts, apoptosis, and secretion of biomolecules. Results are compiled into a TIMING dataset that reveals functional heterogeneity across thousands of cells. The platform also enables selection of cells of interest for downstream multi‑omic profiling, such as single‑cell RNA sequencing or flow cytometry, providing an integrated view of functional performance and molecular state.
Target Audience
Primary customers are biopharmaceutical companies and research groups developing cell‑based immunotherapies who need high‑throughput functional screening of immune cells, as well as academic labs studying cellular dynamics and phenotype.
Features
- Nanowell grid format allows parallel imaging of thousands of individual cells in a single assay
- Visual AI automatically segments, tracks, and quantifies cell migration, contact dynamics, apoptosis, and cytokine secretion
- Time‑lapse fluorescent microscopy captures dynamic behavior as a function of time
- Bead‑based sensors provide real‑time imaging of secreted biomolecules
- Integrated workflow to identify cells of interest and link functional data with single‑cell RNA‑seq or flow cytometry profiles
- Cloud‑based analytics pipeline aggregates and visualizes spatiotemporal performance metrics across the dataset
- Patent‑protected technology ensures proprietary AI models and assay designs