CAVIGEN UG offers microcavity array platforms that recreate physiological oxygen gradients for 3D cell cultures. Their SensoSphere technology integrates oxygen-sensing fluorophores for real-time, localized oxygen measurement, enhancing the accuracy of drug screening and disease modeling.
Funding
Funding not disclosed
Founders
Product
Problem
Current _in vitro_ cell culture systems often fail to replicate the physiological oxygen gradients present in living organisms, leading to inaccurate drug efficacy testing and compromised disease modeling. This discrepancy between _in vitro_ and _in vivo_ conditions results in unreliable research outcomes and hinders the development of effective therapeutics.
Solution
CAVIGEN UG provides advanced microcavity array platforms designed to recreate _in vivo_-like oxygen environments for 3D cell cultures. Their SensoSphere technology integrates oxygen-sensing fluorophores directly into the microcavities, enabling real-time, localized oxygen measurement within the cellular microenvironment. This capability allows researchers to validate and optimize oxygen conditions for spheroid and organoid cultivation, thereby enhancing the physiological relevance and reproducibility of their experiments. By offering a standardized approach to mimicking _in vivo_ oxygen dynamics, CAVIGEN facilitates more accurate drug screening and robust disease modeling.
Target Audience
The primary customers are researchers and scientists in the pharmaceutical and biotechnology sectors, as well as academic institutions, focused on 3D cell culture, drug development, and disease modeling.
Features
- Microcavity arrays engineered for spheroid and organoid generation and cultivation, optimized for microscopy and standardized assays.
- SensoSphere arrays feature integrated oxygen-sensitive fluorophores for direct measurement of oxygen levels within the cellular microenvironment.
- PoroSphere arrays are specifically designed for co-culture applications, facilitating complex cellular interactions.
- Technology supports the replication of physiological oxygen gradients, crucial for mirroring _in vivo_ cellular behavior.
- Enables direct, localized oxygen quantification, improving the accuracy of drug testing and disease modeling.
- Designed for high-throughput screening and enhanced experimental reproducibility.