Cascade develops stabilized, cell-free biocatalysts using proprietary silica bead immobilization technology to enhance enzyme performance. Their Body Armor for Enzymes™ significantly improves temperature, solvent, and pH stability for various enzymes like lipases and carbonic anhydrase. This platform enables longer-lasting, versatile biocatalysts that integrate directly into existing chemical, food, pharma, and waste management processes.
Funding
$2.6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.

Founders
Product
Problem
Many industrial biomanufacturing processes rely on enzymes that are unstable, expensive, and difficult to reuse, leading to high operational costs and limited process flexibility. Traditional enzyme immobilization techniques often fail to provide sufficient protection against harsh process conditions, resulting in reduced enzyme activity and short lifespans.
Solution
Cascade Bio has developed a patented enzyme immobilization platform that enhances the performance and longevity of biocatalysts. The technology stabilizes enzymes on silica beads, creating reusable biocatalysts that can be easily integrated into existing biomanufacturing processes. This "Body Armor for Enzymes™" improves enzyme stability, widens the operating window, and boosts output, leading to more efficient and cost-effective biomanufacturing. The immobilized enzymes offer improved resistance to temperature, solvent, and pH variations, enabling their use in a wider range of industrial applications.
Target Audience
The primary customers are companies in the food, chemicals, waste management, and pharmaceutical industries that utilize enzymes in their manufacturing processes.
Features
- Silica bead-based immobilization platform for enhanced enzyme stability and reusability
- Increased enzyme resistance to temperature, solvent, and pH variations
- Drop-in compatibility with existing biomanufacturing processes
- Demonstrated 100% success rate in improving the stability of 17 different enzymes
- Available immobilized lipases and carbonic anhydrase
- Custom resin development for specific enzyme stabilization needs