This biotechnology company is developing bile acid-based therapies that enhance the body's natural mechanisms for regulating bowel function. Their treatments target chronic idiopathic constipation, irritable bowel syndrome with constipation, and other colon-related conditions, including inflammatory bowel disease and metabolic disorders.
Funding
$17.9M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.

Founders
Product
Problem
Many individuals suffer from chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C), which significantly impact their quality of life. Current treatments often fail to fully address the underlying mechanisms regulating bowel function, leading to inadequate relief and potential side effects. Inflammatory bowel disease (IBD) and metabolic disorders can also manifest with colon-related complications requiring targeted therapeutic interventions.
Solution
Bilayer Therapeutics is developing bile acid-based therapies designed to enhance the body's natural processes for regulating bowel function. Their approach focuses on modulating bile acid signaling pathways to improve colonic motility and alleviate constipation-related symptoms. By targeting the root causes of bowel dysfunction, Bilayer aims to provide more effective and sustainable relief for patients with CIC, IBS-C, and other colon-related conditions. These therapies are also being explored for their potential in managing inflammatory bowel disease and metabolic disorders.
Target Audience
The primary target audience includes individuals suffering from chronic idiopathic constipation, irritable bowel syndrome with constipation, and other colon-related conditions, as well as physicians specializing in gastroenterology and related fields.
Features
- Bile acid-based formulations designed to target specific receptors in the colon
- Modulation of bile acid signaling pathways to enhance colonic motility
- Potential application in treating chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C)
- Investigational therapies for inflammatory bowel disease (IBD) and metabolic disorders