Basilard BioTech develops Celletto™, a novel nanomechanical gene delivery platform for Cell and Gene Therapy (CGT) engineering. This mechanoporation solution delivers genes to the cell nucleus efficiently without compromising viability. Celletto™ addresses manufacturing bottlenecks by offering a more scalable and cost-effective alternative to traditional viral and non-viral gene delivery methods.
Funding
$8.3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current viral vector-based gene delivery methods for cell and gene therapies face limitations in scalability, high costs, and supply chain constraints. Existing non-viral delivery technologies often suffer from low efficiency, safety concerns, and limited versatility in delivering genes to the nucleus of cells.
Solution
Basilard BioTech offers Celletto™, a mechanoporation platform designed to overcome the bottlenecks in cell and gene therapy manufacturing. This technology employs a deterministic mechanoporation (DMP) approach to enable efficient, non-viral gene delivery directly to the nucleus of cells while maintaining high cell viability. Celletto™ utilizes a mechanical process rather than biological or chemical methods, offering a cost-effective and scalable solution for engineering cell-based therapies. The platform's key innovation lies in its ability to deliver virtually any gene en masse without compromising cell integrity, presenting a paradigm shift in cell engineering.
Target Audience
The primary target audience includes cell and gene therapy manufacturers, researchers, and clinical organizations seeking to improve the efficiency and scalability of their gene delivery processes.
Features
- Nanomechanical gene delivery via deterministic mechanoporation (DMP)
- Single-site poration for targeted gene introduction
- Direct nuclear delivery, enhancing transfection efficiency
- Massive parallelization for high-throughput cell processing
- Rapid cell processing capabilities
- Simplified operation for ease of use