AssayQuant Technologies develops PhosphoSens® technology, which provides real-time, continuous measurements of enzyme activity for kinase and phosphatase assays under physiologically relevant conditions. This technology enables precise characterization of drug targets and assessment of compound potency, addressing the need for more effective tools in drug discovery and development.
Funding
$11.6M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current methods for measuring kinase and phosphatase activity in drug discovery and development often lack the ability to provide real-time, continuous measurements under physiologically relevant conditions. Traditional assays may not accurately capture the complete enzymatic reaction, hindering effective characterization of drug targets and assessment of compound potency. This can lead to suboptimal decisions in target biology and the selection of lead candidates.
Solution
AssayQuant Technologies provides PhosphoSens® technology, a platform for real-time, continuous measurement of enzyme activity for kinase and phosphatase assays. This technology enables direct monitoring of the complete reaction, providing kinetic data under physiologically relevant conditions. PhosphoSens® technology utilizes proprietary Sox sensors and can be applied to complex biological samples, such as cell lysates. The assays are designed for simple add-and-read workflows using standard fluorescence microplate readers, providing progress curves in every well. AssayQuant offers substrates and reagents, kinome profiling services, compound testing services, and custom assay development to support drug discovery and development.
Target Audience
The primary target audience includes researchers in academia, biotechnology, and pharmaceutical companies involved in drug discovery and development, particularly those focused on kinase and phosphatase inhibitors.
Features
- Proprietary PhosphoSens® technology for real-time, continuous measurement of kinase and phosphatase activity
- Direct measurement of phosphorylation, capturing the complete enzymatic reaction
- Assays mimic physiological conditions and are amenable to complex samples like cell lysates
- Simple add-and-read workflow compatible with standard fluorescence microplate readers
- Continuous assays that can distinguish covalent from reversible inhibitors based on residence time
- Kinome profiling services for compound selectivity analysis
- Custom assay development for specific research needs
- Both kinetic (continuous) and endpoint (TRF) assay formats available