Arima Genomics utilizes 3D genomics and Hi-C technology to provide detailed insights into the sequence, structure, and regulatory landscape of genomes, enabling the identification of novel biomarkers and therapeutic targets. Their solutions facilitate rapid genome assembly and analysis, addressing the need for comprehensive genomic characterization in cancer research and human health.
Funding
$10.7M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
GHLVFounders
Product
Problem
Traditional genomic analysis often overlooks the critical role of genome structure in gene regulation and disease development. Existing next-generation sequencing methods provide a linear view of the genome, failing to capture the three-dimensional organization that influences cellular function. This limitation hinders the comprehensive identification of biomarkers, therapeutic targets, and disease mechanisms.
Solution
Arima Genomics provides 3D genomics solutions based on Hi-C technology to reveal the sequence, structure, and regulatory landscape of the genome. Their end-to-end solutions enable researchers and clinicians to explore genome-wide chromatin conformation, dynamic gene regulatory mechanisms, and structural variants. By capturing the three-dimensional arrangement of DNA, Arima Genomics' technology facilitates the discovery of novel biomarkers, expands the understanding of disease mechanisms, and supports the development of therapeutic approaches. The company offers a range of products and services, including genome-wide HiC, HiChIP, custom capture HiC, promoter capture HiC, genome assembly HiC, and single-cell Methyl-3C service, along with the Arima Bioinformatics Platform for data analysis and interpretation.
Target Audience
Arima Genomics serves researchers and clinicians in cancer genomics, human health, epigenetics, and genome assembly, as well as biopharmaceutical companies needing support for patient enrollment in clinical trials.
Features
- Genome-wide HiC assays to explore chromatin conformation
- HiChIP assays to discover dynamic gene regulatory mechanisms
- Custom Capture HiC for targeted region analysis with high resolution
- Promoter Capture HiC using established panels to explore gene regulation in humans or mice
- Genome Assembly HiC to enhance next-generation sequencing data
- Single Cell Methyl-3C Service to classify individual cell sub-types
- Arima Bioinformatics Platform for streamlined NGS data analysis, interpretation, and reporting
- HiC FFPE solutions optimized for challenging FFPE samples
- Arima SV Detection Assay for consistent, hypothesis-free detection of structural variants