Avvio Medical provides an office‑based lithotripsy system that uses low‑pressure ultrasound and calcium‑targeted microbubbles to fragment kidney and ureteral stones without anesthesia or stents. The portable console integrates real‑time imaging, automated safety interlocks, and a dedicated CPT code, enabling urologists and ambulatory surgery centers to perform same‑day, cost‑effective stone removal in standard examination rooms.
Funding
Funding not disclosed
Founders
Product
Problem
Patients with urinary stone disease often require hospital-based lithotripsy that involves general anesthesia, ureteral stenting, and prolonged scheduling delays, limiting access for outpatient and rural providers and increasing overall treatment costs.
Solution
Avvio Medical offers an office‑based lithotripsy system that uses low‑pressure ultrasound to activate a proprietary calcium‑seeking microbubble suspension. The microbubbles collapse into high‑velocity micro‑jets that mechanically comminute stones, eliminating the need for anesthesia and indwelling stents. The procedure can be performed in a standard examination room, reducing patient wait times from weeks to days and enabling same‑day stone passage. By avoiding operating‑room resources and postoperative care, the platform lowers per‑case expenditures while maintaining clinical efficacy. The system is supported by FDA Breakthrough Device Designation and a newly published CPT code, facilitating reimbursement and rapid adoption in ambulatory settings.
Target Audience
Primary customers are urologists and ambulatory surgery centers seeking a minimally invasive, anesthesia‑free solution for kidney and ureteral stones, as well as rural health clinics that require a compact, cost‑effective lithotripsy platform.
Features
- Low‑pressure ultrasound transducer calibrated to generate controlled cavitation fields for precise stone fragmentation
- Calcium‑targeted microbubble formulation that preferentially adheres to mineralized surfaces, producing focused micro‑jet impact on calculi
- Integrated real‑time ultrasound imaging for intra‑procedural monitoring of fragment size and location
- Portable, clinic‑grade console with automated safety interlocks and user‑friendly touchscreen workflow
- Automated data capture and secure transmission compliant with HIPAA and FDA regulations for audit‑ready documentation
- Compatibility with existing urology practice management systems via the newly assigned CPT code for streamlined billing
- Clinical validation from the AEROLITH randomized trial demonstrating reduced complication rates compared with conventional laser lithotripsy