Ampersand Biomedicines utilizes its proprietary Address, Navigate, Design (AND) Platform to create AND-Body Therapeutics that precisely target disease sites while minimizing effects on healthy tissues. This technology addresses the challenge of off-tissue side effects in drug development by enabling localized drug delivery through optimized localizer targets.
Funding
$50M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
A significant challenge in drug development is creating therapies that effectively target disease sites without affecting healthy tissues, leading to off-tissue side effects and toxicities. The inability to precisely target diseased areas limits the efficacy and tolerability of many potent therapeutic mechanisms.
Solution
Ampersand Biomedicines addresses this challenge with its Address, Navigate, Determine (AND) Platform, designed to create AND-Body Therapeutics that act precisely where needed in the body. These next-generation modular medicines combine a localizing element for disease-specific precision with an actuator specifically chosen for disease modification. The localizer anchors the medicine in the diseased tissue, while the actuator signals to restore healthy biology, improving target engagement and minimizing off-target effects. The AND Platform utilizes a computationally powered approach and a proprietary Address Map to identify ideal addresses for drug localization and inform the design of AND-Body Therapeutics, resulting in programmed biologics that target disease with improved safety and efficacy.
Target Audience
Ampersand Biomedicines targets pharmaceutical companies and research institutions focused on developing safer and more effective therapeutics with improved targeting capabilities.
Features
- AND-Body Therapeutics: Multi-specific medicines designed to act at the site of disease.
- Address, Navigate, Determine (AND) Platform: Identifies optimal addresses for drug localization.
- Address Map: A proprietary map used to identify localizing targets for any organ, cell, and disease.
- Modular Design: Combines localizing elements with actuator elements for targeted disease modification.
- Computationally Powered: Utilizes computational methods to enhance therapeutic effect.