The startup develops natural and synthetic bone graft substitutes that integrate the osteoinductive properties of demineralized bone with the osteostimulative effects of 45S5 bioactive glass. This technology enhances the healing and regenerative capacity of bone grafts in orthopedic, spine, and dental surgeries, improving patient outcomes in bone healing.
Funding
$2.3M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
Founders
Product
Problem
Current options for wound closure and protection in oral and dental surgeries, such as sutures, glues, and resins, can be difficult to apply, offer limited protection, or lack long-lasting adhesion in wet and mechanically challenging environments. Bone void fillers may lack the necessary properties to facilitate strong bonding and effective bone regeneration.
Solution
Amend Surgical develops bio-inspired adhesive and regenerative technologies for dental and surgical applications. Their TissueTape product, a biocompatible hydrogel and chitosan-based surgical glue, provides long-lasting adhesion and barrier protection for oral wounds, adhering to wet, uneven surfaces and offering an alternative to traditional sutures and short-acting glues. Tissure, another hydrogel and chitosan-based glue, is designed for suture-less nerve repair. NanoFUSE Bioactive Matrix combines bioactive glass and demineralized allograft bone to enhance bone regeneration in orthopedic and spinal fusion procedures, facilitating a strong bond between the graft and adjacent bony tissue.
Target Audience
The primary target audience includes oral and maxillofacial surgeons, periodontists, and other dental professionals performing soft and hard tissue regenerative procedures, as well as orthopedic and spine surgeons requiring advanced bone void fillers.
Features
- **TissueTape:**
- Non-resorbable hydrogel and surgical glue for oral wound protection.
- Composed of alginate and polyacrylamide hydrogel with chitosan adhesive.
- Adheres gently for repositioning, then tightly bonds to wet soft tissue.
- Demonstrates adhesion energy five times greater than cyanoacrylate.
- Easily removed without disrupting underlying tissue.
- **Tissure:**
- Biocompatible hydrogel and chitosan-based glue and resorbable barrier.
- Designed for suture-less peripheral nerve repair.
- **NanoFUSE Bioactive Matrix:**
- Combines calcium-based 45S5 bioactive glass with demineralized allograft bone.
- Bioactive glass creates a strong chemical bond with tissue.
- Demineralized allograft bone supports cell attachment and proliferation.
- Contains DBM that is 100% tested for osteoinductive potential.
- Gelatin precipitation method for ease of preparation and shaping.