ALZpath provides a proprietary pTau217 antibody that enables highly sensitive, blood‑based detection of Alzheimer’s disease pathology, matching the accuracy of PET scans and CSF tests. By licensing this antibody to diagnostic manufacturers and laboratories, it allows the development of non‑invasive assays that can identify disease up to 15 years before symptoms, facilitating earlier clinical decision‑making.
Funding
Funding not disclosed
Founders
Product
Problem
Alzheimer’s disease is often diagnosed at advanced stages because current methods rely on invasive cerebrospinal fluid collection, expensive imaging, or long laboratory turnaround times, limiting early intervention.
Solution
ALZpath supplies a proprietary pTau217 antibody that enables highly sensitive and specific detection of Alzheimer’s pathology through a simple blood draw. The antibody is licensed to diagnostic and life‑science companies, allowing them to develop blood‑based assays that match the accuracy of PET scans and CSF tests. By detecting phosphorylated tau 217 up to 15 years before clinical symptoms, these assays provide clinicians and patients with earlier, actionable information. The approach is non‑invasive, scalable, and compatible with existing laboratory platforms, facilitating widespread adoption across healthcare settings.
Target Audience
Primary customers are diagnostic manufacturers, clinical laboratories, and healthcare providers seeking to offer early, blood‑based Alzheimer’s testing.
Features
- Proprietary pTau217 antibody targeting a protein modification that appears early in Alzheimer’s disease
- Blood‑based assay performance comparable to PET imaging and CSF biomarkers
- Ability to detect disease pathology up to 15 years prior to symptom onset
- Licensed to major diagnostic manufacturers (e.g., Beckman Coulter, Roche, Siemens Healthineers) for rapid market integration
- Compatible with CAP/CLIA‑certified laboratories, ensuring consistent and reliable testing
- Non‑invasive sample collection requiring only a standard venous blood draw