Akadeum develops the Alerion™ Microbubble Cell Separation System, which utilizes microbubble technology for negative selection and cell depletion workflows to isolate healthier cells from biological samples. This system enhances cell viability and recovery while increasing scalability, addressing the need for more efficient and effective cell therapy manufacturing processes.
Funding
Funding not disclosed
+2Founders
Product
Problem
Current cell separation techniques often damage cells, require specialized equipment, and lack scalability, hindering efficient cell therapy manufacturing and research. Traditional methods can also be time-consuming and expensive, limiting throughput and increasing costs.
Solution
Akadeum Life Sciences provides a microbubble cell separation platform that enables gentle and efficient isolation of healthier cells from biological samples. The company's Buoyancy Activated Cell Sorting (BACS™) technology uses microbubbles coated with affinity molecules to selectively capture target cells, which then float to the surface for easy removal, leaving behind the enriched sample. This method enhances cell viability and recovery, increases scalability, and integrates seamlessly into existing workflows, reducing the footprint and cost of cell separation processes. Akadeum's technology can be used for positive selection, negative selection, and cell depletion workflows.
Target Audience
Akadeum's primary customers are cell therapy manufacturers, researchers in immunology and cell biology, and clinical labs seeking efficient and scalable cell separation solutions.
Features
- Microbubble technology for gentle and efficient cell separation, preserving cell viability and functionality
- BACS™ platform enables scalable cell separation from small research volumes to large manufacturing scales
- Negative selection capability allows for isolation of untouched and unbiased cell populations
- Alerion™ Microbubble Cell Separation System enables negative selection of entire leukopaks in under an hour
- Kits available for T cell isolation, B cell isolation, PBMC isolation, and dead cell removal
- GMP-grade and Clinical-Ready products available for cell therapy applications
- Seamless integration into existing workflows with minimal specialized equipment required
- Customizable with a variety of bio-analytes to target specific cell groups