Ailurus Biotechnology provides a synthetic biology platform that utilizes DNA-encoded programs to miniaturize laboratory functions within living cells, enabling the in vivo expression and purification of tag-less proteins in a single reaction. This technology enhances protein yield and quality while allowing for scalable and high-throughput projects, addressing the inefficiencies of traditional protein purification methods.
Funding
Funding not disclosed
Founders
Product
Problem
Traditional protein purification methods are inefficient, often resulting in low yields and compromised protein quality, hindering scalable and high-throughput projects. Existing techniques rely on column or magnetic bead separation, which can be labor-intensive and introduce unwanted tags to the purified proteins.
Solution
Ailurus Biotechnology offers a synthetic biology platform that leverages DNA-encoded programs to miniaturize laboratory functions within living cells, enabling in vivo expression and purification of tag-less proteins in a single reaction. This technology allows for the recovery of highly purified proteins directly from the host organism, eliminating the need for traditional column-based or magnetic bead separation methods. By autonomizing the expression and purification process using synthetic organelle pathways, Ailurus's platform broadens the scope of protein isolation, leading to improved yields and enhanced protein quality. The platform is designed for projects at varying volumes and supports high-throughput applications, facilitating accelerated biological research and development.
Target Audience
Ailurus Biotechnology serves researchers and companies in the biotechnology, pharmaceutical, and synthetic biology sectors seeking efficient, scalable, and high-quality protein production methods.
Features
- DNA-encoded programs for in vivo protein expression and purification
- Automated protein purification within living cells, eliminating the need for external separation methods
- Production of tag-less proteins, preserving native protein structure and function
- Synthetic organelle pathways for autonomized expression and purification
- Scalable platform suitable for both low-volume and high-throughput projects
- Enhanced protein yield and quality compared to traditional methods
- Capability to isolate proteins from various hosts
- TEAR-2 development kit for engineering phase separations and spatially controlling intracellular reactions