Adona Medical develops a novel interatrial shunt with integrated bi-atrial pressure monitoring to enable real-time adjustments for individualized heart failure management. This technology directly measures left and right atrial pressures, allowing for precise control of shunt lumen size to alleviate heart failure symptoms.
Funding
$95.5M raised to dateRaised to date based on public sources. This may differ from the amount the company actually raised and is based only on what is publicly available on the internet.
CATHFounders
Product
Problem
Heart failure management is often hampered by the inability to continuously monitor and adjust to changing bi-atrial pressures, leading to suboptimal symptom control and disease progression. Current methods lack the ability to dynamically optimize interatrial shunting based on real-time physiological data.
Solution
Adona Medical is developing an interatrial shunt with integrated bi-atrial pressure monitoring to enable individualized heart failure management. The shunt directly measures left and right atrial pressures, providing clinicians with real-time data to optimize shunt flow. The shunt lumen can be adjusted post-implantation, allowing for precise control of blood flow between the atria to alleviate heart failure symptoms. This technology aims to provide a more dynamic and responsive approach to managing heart failure by enabling flow adjustments over time.
Target Audience
The primary target audience includes cardiologists and interventional cardiologists specializing in heart failure management, as well as patients with heart failure who are candidates for interatrial shunting.
Features
- Integrated bi-atrial pressure sensors for direct left atrial (LA) and right atrial (RA) pressure readings, targeting 5+ automated readings per day.
- Adjustable shunt lumen designed to be enlarged or reduced post-implant, with a target diameter of 5-10 mm and temporary opening to 14mm for left-heart access.
- Shape memory nitinol shunt material chosen for malleable attributes at body temperature, returning to nominal size with brief energy application.
- ePTFE encased anchor for biocompatible insulation to encourage healthy tissue response.
- Lumen enlargement achieved with a balloon catheter.
- Lumen reduction achieved with the Adona Induction Catheter, which uses non-contact inductive energy transfer to heat only targeted, insulated areas of the shunt.